The SCD5 Antibody (Center) from MyBioSource.com is a Rabbit Polyclonal antibody to SCD, SCD1, SCD2, sCD4, and SCD5. This antibody recognizes Human antigen. The SCD5 Antibody (Center) has been validated for the following applications: ELISA, and Western Blot.
Description
Stearoyl-CoA desaturase (SCD; EC 1.14.99.5) is an integral
membrane protein of the endoplasmic reticulum that catalyzes the
formation of monounsaturated fatty acids from saturated fatty
acids. SCD may be a key regulator of energy metabolism with a role
in obesity and dislipidemia. Four SCD isoforms, Scd1 through Scd4,
have been identified in mouse. In contrast, only 2 SCD isoforms,
SCD1 (MIM 604031) and SCD5, have been identified in human. SCD1
shares about 85% amino acid identity with all 4 mouse SCD isoforms,
as well as with rat Scd1 and Scd2. In contrast, SCD5 shares limited
homology with the rodent SCDs and appears to be unique to primates
(Wang et al., 2005 [PubMed 15907797])